Sat Mar 23, 2024 11:33 pm by globalturbo
Friday, October 19, 2012
Turmeric Compound Reduces Post-Bypass Heart Attack Risk 56%
Sayer Ji, Contributor
Activist Post
A remarkable study performed at Chiang Mai University, Thailand and published in the American Journal of Cardiology
last July, found that the administration of curcuminoids, natural
phenols within the spice turmeric, reduced the frequency of myocardial
infarction (heart attack) after coronary artery bypass in a group of 121
patients randomly selected to receive a placebo or 4 grams a day
beginning 3 days before the scheduled surgery and continued until 5 days
after surgery.
According to the study, "it is well established that myocardial
infarction (MI) associated with coronary artery bypass grafting (CABG)
predicts a poor outcome. Nevertheless, cardioprotective therapies to
limit myocardial injury after CABG are lacking." The researchers
hypothesized that since preclinical research shows curcuminoids decrease
proinflammatory cytokines during cardiopulmonary bypass surgery and
decrease the occurrence of cardiac cell death, they may provide a
much-needed therapy.
The primary end point was the incidence of in-hospital myocardial
infarction, which was found to be decreased from 30.0% in the placebo
group to 13.1% in the curcuminoid group -- a 56% relative risk reduction.
The secondary end point was the effect of
curcuminoids on C-reactive protein, plasma maondialdehyde, and
N-terminal pro-B-type naturietic peptide levels, all of which were lower
after treatment.
The study authors concluded: "we demonstrated that curcuminoids
significantly decreased MI associated with CABG. The antioxidant and
anti-inflammatory effects of curcuminoids may account for their
cardioprotective effects shown in this study."
Curcumin is one of the world's most thoroughly studied and characterized
phytocompounds, with thousands of studies published in peer-reviewed
biomedical journals, and dozens of researched applications to
cardiovascular health. There are 34 studies on our database indicating curcumin's cardioprotective properties, 55 studies on its ability to down-regulate the Cox-2 enzyme,
which is associated with inflammatory processes directly linked to the
underlying causes of cardiovascular disease, and 205 studies indicating
its antioxidant properties, which may confer protection against oxidative stress within the cardiovascular system.
Other relevant sections on our database linking curcumin to cardiovascular benefits are:
curcumin's potential value to cardiovascular health, and only a fraction
of the 500+ health benefits of curcumin, and the even larger set of experimentally confirmed health benefits associated with turmeric. To learn more about our Turmeric research project please watch the video below.
[i]
Wanwarang Wongcharoen, Sasivimon Jai-Aue, Arintaya Phrommintikul,
Weerachai Nawarawong, Surin Woragidpoonpol, Thitipong Tepsuwan, Apichard
Sukonthasarn, Nattayaporn Apaijai, Nipon Chattipakorn. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. [i]Am J Cardiol. 2012 Jul 1 ;110(1):40-4. Epub 2012 Apr 3. PMID: 22481014
This article first appeared at GreenMedInfo. Please visit to access their vast database of articles and the latest information in natural health.
Thanks to: http://www.activistpost.com
Turmeric Compound Reduces Post-Bypass Heart Attack Risk 56%
Activist Post
A remarkable study performed at Chiang Mai University, Thailand and published in the American Journal of Cardiology
last July, found that the administration of curcuminoids, natural
phenols within the spice turmeric, reduced the frequency of myocardial
infarction (heart attack) after coronary artery bypass in a group of 121
patients randomly selected to receive a placebo or 4 grams a day
beginning 3 days before the scheduled surgery and continued until 5 days
after surgery.
According to the study, "it is well established that myocardial
infarction (MI) associated with coronary artery bypass grafting (CABG)
predicts a poor outcome. Nevertheless, cardioprotective therapies to
limit myocardial injury after CABG are lacking." The researchers
hypothesized that since preclinical research shows curcuminoids decrease
proinflammatory cytokines during cardiopulmonary bypass surgery and
decrease the occurrence of cardiac cell death, they may provide a
much-needed therapy.
The primary end point was the incidence of in-hospital myocardial
infarction, which was found to be decreased from 30.0% in the placebo
group to 13.1% in the curcuminoid group -- a 56% relative risk reduction.
The secondary end point was the effect of
curcuminoids on C-reactive protein, plasma maondialdehyde, and
N-terminal pro-B-type naturietic peptide levels, all of which were lower
after treatment.
The study authors concluded: "we demonstrated that curcuminoids
significantly decreased MI associated with CABG. The antioxidant and
anti-inflammatory effects of curcuminoids may account for their
cardioprotective effects shown in this study."
Curcumin is one of the world's most thoroughly studied and characterized
phytocompounds, with thousands of studies published in peer-reviewed
biomedical journals, and dozens of researched applications to
cardiovascular health. There are 34 studies on our database indicating curcumin's cardioprotective properties, 55 studies on its ability to down-regulate the Cox-2 enzyme,
which is associated with inflammatory processes directly linked to the
underlying causes of cardiovascular disease, and 205 studies indicating
its antioxidant properties, which may confer protection against oxidative stress within the cardiovascular system.
Other relevant sections on our database linking curcumin to cardiovascular benefits are:
- Curcumin and Cardiac Mortality
- Curcumin and Cardiac Hypertrophy
- Curcumin and Cardiomegaly
- Curcumin and Carotid Artery Narrowing
- Curcumin and Cerebral Ischemia (Stroke)
- Curcumin and Endothelial Dysfunction
- Curcumin and Heart Failure
- Curcumin and High Cholesterol
- Curcumin and Elevated Homocysteine
- Curcumin and Left Ventricular Hypertrophy
- Curcumin and Hypertension
- Curcumin and Hyperlipidemia
- Curcumin and Aortic Stenosis
- Curcumin and Atherosclerosis
- Curcumin and Heart Attack
- Curcumin and Viral Myocarditis
- Curcumin and Stroke Recovery
curcumin's potential value to cardiovascular health, and only a fraction
of the 500+ health benefits of curcumin, and the even larger set of experimentally confirmed health benefits associated with turmeric. To learn more about our Turmeric research project please watch the video below.
[i]
Wanwarang Wongcharoen, Sasivimon Jai-Aue, Arintaya Phrommintikul,
Weerachai Nawarawong, Surin Woragidpoonpol, Thitipong Tepsuwan, Apichard
Sukonthasarn, Nattayaporn Apaijai, Nipon Chattipakorn. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. [i]Am J Cardiol. 2012 Jul 1 ;110(1):40-4. Epub 2012 Apr 3. PMID: 22481014
This article first appeared at GreenMedInfo. Please visit to access their vast database of articles and the latest information in natural health.
Thanks to: http://www.activistpost.com
