“Key Covid Vaccine ingredient causes deadly Diseases”: Salk Institute Study
Salk Institute Report Circulation Research, + Covid Questions by Mike Whitney – 3 May 2021
“The risk-benefit calculus is therefore clear: the experimental vaccines are needless, ineffective and dangerous. Actors authorizing, coercing or administering experimental COVID-19 vaccination are exposing populations and patients to serious, unnecessary, and unjustified medical risks.” Doctors for Covid Ethics, April 29, 2021.
Representative images of vascular endothelial control cells (left) and cells treated with the SARS-CoV-2 Spike protein (right) show that the spike protein causes increased mitochondrial fragmentation in vascular cells.
Click here for a high-resolution image.
Credit: Salk Institute
But these same spike proteins are a key part of the vaccines as well, and do their damage even without any Covid virus being present. ..
” the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls”.
The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. The findings help explain COVID-19’s wide variety of seemingly unconnected complications, and could open the door for new research into more effective therapies.
Simply put, if Covid-19 is primarily a vascular disease and if the main instrument of physical damage is the spike protein, then why are we injecting people with billions of spike proteins?
“A lot of people think of it as a respiratory disease, but it’s really a vascular disease,” says Assistant Research Professor Uri Manor, who is co-senior author of the study. “That could explain why some people have strokes, and why some people have issues in other parts of the body. The commonality between them is that they all have vascular underpinnings.”
Salk researchers collaborated with scientists at the University of California San Diego on the paper, including co-first author Jiao Zhang and co-senior author John Shyy, among others..
While the findings themselves aren’t entirely a surprise, the paper provides clear confirmation and a detailed explanation of the mechanism through which the protein damages vascular cells for the first time. There’s been a growing consensus that SARS-CoV-2 affects the vascular system, but exactly how it did so was not understood.
Similarly, scientists studying other coronaviruses have long suspected that the spike protein contributed to damaging vascular endothelial cells, but this is the first time the process has been documented.
The new research paper is the equivalent of a hydrogen bomb. It changes everything by confirming what vaccine critics have been theorizing for months but were unable to prove.
“In the new study, the researchers created a “pseudovirus” that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model—proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls”.
The team then replicated this process in the lab, exposing healthy endothelial cells (which line arteries) to the spike protein. They showed that the spike protein damaged the cells by binding ACE2. This binding disrupted ACE2’s molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented.
Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own.
“If you remove the replicating capabilities of the virus, it still has a major damaging effect on the vascular cells, simply by virtue of its ability to bind to this ACE2 receptor, the S protein receptor, now famous thanks to COVID,” Manor explains. “Further studies with mutant spike proteins will also provide new insight towards the infectivity and severity of mutant SARS CoV-2 viruses.”
The researchers next hope to take a closer look at the mechanism by which the disrupted ACE2 protein damages mitochondria and causes them to change shape.
PUBLICATION INFORMATION JOURNAL
Circulation Research
TITLE SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2
AUTHORS
Yuyang Lei, Jiao Zhang, Cara R Schiavon, Ming He, Lili Chen, Hui Shen, Yichi Zhang, Qian Yin, Yoshitake Cho, Leonardo Andrade, Gerald S Shadel, Mark Hepokoski, Ting Lei, Hongliang Wang, Jin Zhang, Jason X-J Yuan, Atul Malhotra, Uri Manor, Shengpeng Wang, Zu-Yi Yuan, and John Y-J Shyy
DOI: 10.1161/CIRCRESAHA.121.318902
**********************************
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The article, which is titled “The novel coronavirus’ spike protein plays additional key role in illness”, shows that SARS-CoV-2’s “distinctive ‘spike’ protein”..”damages cells, confirming COVID-19 as a primarily vascular disease.” While the paper focuses strictly on Covid-related issues, it unavoidably raises questions about the new vaccines that contain billions of spike proteins that could greatly increase the chances of severe illness or death. Here’s an excerpt from the article dated April 30, 2021:
Now there is solid evidence that:
Simply put, if Covid-19 is primarily a vascular disease and if the main instrument of physical damage is the spike protein, then why are we injecting people with billions of spike proteins?
Here’s how architect and author, Robin Monotti Graziadei, summed up these developments on you tube:
Will they try to sweep it under the rug or will they try to divert the public’s attention to the ‘variant’ hobgoblin? Or will they try something else entirely, like claim that one class of spike proteins are good for you while others lead to protracted illness and death? What will they do?
Immune response to COVID-19’s spike protein
Doctor Vladimir Zelenko, who has been nominated for a Nobel Peace Prize for his use of hydroxychloroquine in the treatment of COVID-19 patients, had this to say: “Do you understand what this means——we are are injecting viral genetic code for the spike protein into innocent people and it gets into almost every cell In the body.” (Nobel nominee, Zelenko has also been banned from Twitter.)
COVID-19 MRNA VACCINE MODERNA (CX-024414) .. .. European Medicines Agency
Indeed, that’s precisely what they’ve done. And, let’s not forget, the vaccine manufacturers have complete legal immunity for the injuries they produce. Legal immunity means moral impunity.
So what effect will these spike proteins have on the people that have gotten vaccinated?
Here’s what the Doctors for Covid Ethics have to say in their latest article that was published just this week:
CONTINUE HERE: https://thefreeonline.wordpress.com/2021/05/04/shock-scientists-find-spike-protein-in-covid-vaccines-could-kill-and-maim-millions/
Thanks to: https://thefreeonline.wordpress.com
Salk Institute Report Circulation Research, + Covid Questions by Mike Whitney – 3 May 2021
“The risk-benefit calculus is therefore clear: the experimental vaccines are needless, ineffective and dangerous. Actors authorizing, coercing or administering experimental COVID-19 vaccination are exposing populations and patients to serious, unnecessary, and unjustified medical risks.” Doctors for Covid Ethics, April 29, 2021.
The novel coronavirus’ Spike Protein plays key role in illness. Prestigious Salk researchers and collaborators show how the protein invades and damages cells by the Vascular System, even without COVID-19 being present.
LA JOLLA—Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that they also play a key role in the disease itself.Representative images of vascular endothelial control cells (left) and cells treated with the SARS-CoV-2 Spike protein (right) show that the spike protein causes increased mitochondrial fragmentation in vascular cells.
Click here for a high-resolution image.
Credit: Salk Institute
But these same spike proteins are a key part of the vaccines as well, and do their damage even without any Covid virus being present. ..
” the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls”.
The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. The findings help explain COVID-19’s wide variety of seemingly unconnected complications, and could open the door for new research into more effective therapies.
Simply put, if Covid-19 is primarily a vascular disease and if the main instrument of physical damage is the spike protein, then why are we injecting people with billions of spike proteins?
“A lot of people think of it as a respiratory disease, but it’s really a vascular disease,” says Assistant Research Professor Uri Manor, who is co-senior author of the study. “That could explain why some people have strokes, and why some people have issues in other parts of the body. The commonality between them is that they all have vascular underpinnings.”
Salk researchers collaborated with scientists at the University of California San Diego on the paper, including co-first author Jiao Zhang and co-senior author John Shyy, among others..
While the findings themselves aren’t entirely a surprise, the paper provides clear confirmation and a detailed explanation of the mechanism through which the protein damages vascular cells for the first time. There’s been a growing consensus that SARS-CoV-2 affects the vascular system, but exactly how it did so was not understood.
Similarly, scientists studying other coronaviruses have long suspected that the spike protein contributed to damaging vascular endothelial cells, but this is the first time the process has been documented.
The new research paper is the equivalent of a hydrogen bomb. It changes everything by confirming what vaccine critics have been theorizing for months but were unable to prove.
“In the new study, the researchers created a “pseudovirus” that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model—proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls”.
The team then replicated this process in the lab, exposing healthy endothelial cells (which line arteries) to the spike protein. They showed that the spike protein damaged the cells by binding ACE2. This binding disrupted ACE2’s molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented.
Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own.
“If you remove the replicating capabilities of the virus, it still has a major damaging effect on the vascular cells, simply by virtue of its ability to bind to this ACE2 receptor, the S protein receptor, now famous thanks to COVID,” Manor explains. “Further studies with mutant spike proteins will also provide new insight towards the infectivity and severity of mutant SARS CoV-2 viruses.”
The researchers next hope to take a closer look at the mechanism by which the disrupted ACE2 protein damages mitochondria and causes them to change shape.
PUBLICATION INFORMATION JOURNAL
Circulation Research
TITLE SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2
AUTHORS
Yuyang Lei, Jiao Zhang, Cara R Schiavon, Ming He, Lili Chen, Hui Shen, Yichi Zhang, Qian Yin, Yoshitake Cho, Leonardo Andrade, Gerald S Shadel, Mark Hepokoski, Ting Lei, Hongliang Wang, Jin Zhang, Jason X-J Yuan, Atul Malhotra, Uri Manor, Shengpeng Wang, Zu-Yi Yuan, and John Y-J Shyy
DOI: 10.1161/CIRCRESAHA.121.318902
**********************************
- US expected to authorise Pfizer COVID jabs for 12 to 15 year olds “The company previously found its shot provided protection for the younger age group”. 4 May 2021
- CDC Officially Recommends COVID Jab for Pregnant Women
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COVID Questions.. An explosive new study by researchers at the prestigious Salk Institute casts doubt on the current crop of gene-based vaccines that may pose a grave risk to public health
https://xenagoguevicene.wordpress.com/2021/05/03/covid-questions-new-report-sheds-light-on-vaccine-doomsday-cult-by-mike-whitney-3-may-2021/The article, which is titled “The novel coronavirus’ spike protein plays additional key role in illness”, shows that SARS-CoV-2’s “distinctive ‘spike’ protein”..”damages cells, confirming COVID-19 as a primarily vascular disease.” While the paper focuses strictly on Covid-related issues, it unavoidably raises questions about the new vaccines that contain billions of spike proteins that could greatly increase the chances of severe illness or death. Here’s an excerpt from the article dated April 30, 2021:
The new research paper is the equivalent of a hydrogen bomb. It changes everything by confirming what vaccine critics have been theorizing for months but were unable to prove.“In the new study, the researchers created a “pseudovirus” that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model—proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls. (Note– “Vascular endothelial cells line the entire circulatory system, from the heart to the smallest capillaries.”)
The team then replicated this process in the lab, exposing healthy endothelial cells (which line arteries) to the spike protein. They showed that the spike protein damaged the cells by binding ACE2. This binding disrupted ACE2’s molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented.
Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own.” (“The novel coronavirus’ spike protein plays additional key role in illness”, Salk.edu)
Now there is solid evidence that:
- Covid-19 is primarily a disease of the vascular system (The vascular system, also called the circulatory system, is made up of the vessels that carry blood and lymph through the body.) and not the respiratory system.
- The main culprit is the spike protein. (Spike protein–“a glycoprotein that protrudes from the envelope of some viruses” Merriam-Webster “Like a key in a lock, these spike proteins fuse to receptors on the surface of cells, allowing the virus’s genetic code to invade the host cell, take over its machinery and replicate.” Bruce Lieberman)
Simply put, if Covid-19 is primarily a vascular disease and if the main instrument of physical damage is the spike protein, then why are we injecting people with billions of spike proteins?
Here’s how architect and author, Robin Monotti Graziadei, summed up these developments on you tube:
Perfectly stated and right on the money. Graziadei extrapolates the hidden meaning of the Salk report and clarifies its significance. How are the public health officials, the politicians, the media and the rest of the pro-Covid Vaxx camp going to respond to these revelations especially with the imprimatur of the Salk Institute affixed to the front of the report?“So, we have been told for the last year, that the only role the spike protein was supposed to play was to enter the human cells. (But) It’s clear, that that is not what they do, (since) they give you illness, vascular illness. Vascular illness can have many manifestations. They can include sinus vein thrombosis, blood clots, bruising, and longer-term conditions. Do you think it’s a good idea to bypass the first (defenses) of your immune system, …and inject… trillions of spike proteins in your cells given the information that has just been released by the Salk Institute? Think about it….
Salk Institute researchers have told us –without any ambiguity– that the spike protein is a fundamental part of the Covid-19 disease. Yes, it’s true that the spike protein with the N-protein, will not replicate.
However, trillions (of these proteins) induced by the vaccine injection have the capacity to create damage in your vascular system. This is what the study says and what has been published by an extremely important center for biological studies. This is not a conspiracy theory. I think, at this stage, there is enough information to consider whether we will be told the truth in the coming days, because such information should be on the cover of every newspaper and the top story on every news channel.
And what they should say is this: “The fundamental and technological basis –on which all of the vaccines that were distributed in the West– is flawed. We thought that the spike protein would only enter the cells to create antibodies so if you faced the wild virus, it would not latch onto your cells, however, we were wrong.
We were wrong because the spike protein in itself, creates disease, and if you inject trillions of them into a human body, there will be manifestations of disease in many cases.” It is not safe to inject trillions of spike proteins into a muscle, because it bypasses layers of your immune system which could have potentially neutralized the virus…
By crossing the threshold of the human body through the injection of these compounds, you are not giving your immune system the chance to mount a strong enough response to the spike protein in order to neutralize it. (The vaccine) will have this disease-creating spike protein in it if you agree (to take) any of these vaccines. ….
It is now up to us to try to fix the mistake they have made.” (Robin Monotti Graziadei on the new Salk Institute research paper, You Tube, –See it before it is removed)
Will they try to sweep it under the rug or will they try to divert the public’s attention to the ‘variant’ hobgoblin? Or will they try something else entirely, like claim that one class of spike proteins are good for you while others lead to protracted illness and death? What will they do?
Immune response to COVID-19’s spike protein
Doctor Vladimir Zelenko, who has been nominated for a Nobel Peace Prize for his use of hydroxychloroquine in the treatment of COVID-19 patients, had this to say: “Do you understand what this means——we are are injecting viral genetic code for the spike protein into innocent people and it gets into almost every cell In the body.” (Nobel nominee, Zelenko has also been banned from Twitter.)
COVID-19 MRNA VACCINE MODERNA (CX-024414) .. .. European Medicines Agency
Indeed, that’s precisely what they’ve done. And, let’s not forget, the vaccine manufacturers have complete legal immunity for the injuries they produce. Legal immunity means moral impunity.
So what effect will these spike proteins have on the people that have gotten vaccinated?
Here’s what the Doctors for Covid Ethics have to say in their latest article that was published just this week:
There it is in black and white: “The vaccines are not safe”. Here’s more from an article at Children’s Health Defense about Professor Yehuda Shoenfeld, the Israeli clinical immunologist who is widely credited as the “father of autoimmunity.” Shoenfeld approaches the issue from an entirely different angle. Take a look:“The vaccines are dangerous to both healthy individuals and those with pre-existing chronic disease, for reasons such as the following: risk of lethal and non-lethal disruptions of blood clotting including bleeding disorders, thrombosis in the brain, stroke and heart attack; autoimmune and allergic reactions; antibody-dependent enhancement of disease; and vaccine impurities due to rushed manufacturing and unregulated production standards….
…all gene-based vaccines can be expected to cause blood clotting and bleeding disorders…. The vaccines are not safe.” (“COVID Vaccines: Necessity, Efficacy and Safety”, Doctors for Covid Ethics)
My limited understanding of “molecular mimicry”, is this: By injecting proteins into the body that are so similar to the Covid proteins that are wreaking havoc in the vascular system, we could trigger a situation in which the body’s immune system attacks its own organs or vascular system. Which is why the author asks: Are We on the Verge of a ‘Super-Epidemic’ of Autoimmune Diseases?“Shoenfeld’s primary concern boils down to what’s called molecular mimicry. There are a number of genetic sequences that are identical both in the human genome and that of SARS-CoV-2 …
The immunologists go on to draw particular attention to the identical sequences in a specific group of proteins found deep in the lungs (the site of ARDS/covid pneumonia)… This is a concern Shoenfeld …
It’s why Shoenfeld and colleagues have been banging on the drum during the vaccine development phase last year, arguing that peptide sequences used in the new vaccines should be unique and not be common to ones found in the body.
For a predisposed individual, an adverse reaction to the vaccine, Shoenfeld and colleagues argue, could be enough for them to be tipped over the edge — into autoimmune disease. One of the most obvious signals for predisposition is to already have one of the over 100 autoimmune diseases that are charging through industrialized societies.
Yet, with the father of autoimmunity sounding the warnings of autoimmune risks, there is scarcely a word of caution being uttered by governments rolling out the mass vaccination programs. Shame on them.” (“Are We on the Verge of a ‘Super-Epidemic’ of Autoimmune Diseases?” Children’s Health Defense)
CONTINUE HERE: https://thefreeonline.wordpress.com/2021/05/04/shock-scientists-find-spike-protein-in-covid-vaccines-could-kill-and-maim-millions/
Thanks to: https://thefreeonline.wordpress.com