Recombinant Antigens for 2015-2024 Influenza Vaccine Strains

Recombinant Antigens for 2015-2024 Influenza Vaccine Strains



Seasonal flu is a common infectious disease of the respiratory tract caused by influenza virus. There are four types of influenza virus, influenza type A, B, C, and D. The A and B types are of most interest to the medical community because they are the culprits for seasonal epidemics. Occasionally, influenza A, like the A/California/04/09 (H1N1) and A/Hong Kong/1/1968 (H3N2), can even cause global pandemics.
Vaccination is the most effective way to prevent flu infection. Each year, several different flu strains are selected as vaccine candidates based on surveillance data of the recent isolates and the performance of the vaccines from the previous season. In recent decades, most influenza vaccines are trivalent or quadrivalent, composed of one H1N1, one H3N2, and either one or two type B viruses (Yamagata and Victoria lineage).

Sino Biological offers recombinant flu antigen products under its ProVir viral antigen collection. The product line covers Hemagglutinin (HA), Neuraminidase (NA), and Nucleoprotein (NP) proteins, from all WHO-recommended vaccine strains in recent years. These antigens can be used to analyze vaccine-induced antibody response. In addition, Sino Biological also develops a large collection of monoclonal antibodies against the flu antigens. These reagents can help facilitate relevant assay development.

 Year 2023-2024

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  A/Victoria/4897/2022 (H1N1)

  Recommended for Egg-based (quadrivalent,trivalent) Vaccine

  HA: 40938-V08H (pre-order), 40938-V08B (pre-order)

  NA: 40939-V08B (pre-order), 40941-V08B (pre-order)

  
  

  A/Darwin/9/2021 (H3N2)

  Recommended for Egg-based, Cell- or recombinant-based (quadrivalent, trivalent) Vaccine

  HA: 40859-V08B, 40859-V08H

  NA: 40860-V08B

  NP: 40858-V08B

  
  

  B/Austria/1359417/2021 (B/Victoria lineage)

  Recommended for Egg-based, Cell- or recombinant-based (quadrivalent, trivalent) Vaccine

  HA: 40862-V08B, 40862-V08H

  NA: 40863-V08B

  NP: 40861-V08B

  
  

  A/Wisconsin/67/2022 (H1N1)

  Recommended for Cell- or recombinant-based (quadrivalent, trivalent) Vaccine

  HA: 40940-V08H (pre-order), 40940-V08B (pre-order)

  NA: 40941-V08B (pre-order)

  NP: 40942-V08B (pre-order)

  
  

  B/Phuket/3073/2013 (B/Yamagata lineage)

  Recommended for Egg-based, Cell- or recombinant-based (quadrivalent) Vaccine

  HA: 40498-VNAB, 40498-V08B, 40498-V08H1

  NA: 40502-V07B

  NP: 40500-V08B

  
  

CONTINUE HERE: https://www.sinobiological.com/research/virus/influenza-vaccine-strains-2015-2021?utm_source=livescience&utm_medium=newsletter&utm_campaign=mar-influenza